The novel Coronavirus Sars-CoV-2 triggered a pandemic brings, in particular, Pregnant women in a difficult Situation. In addition to the risk of infection, the anxious question for you: Can cause damage to the pathogen is the Unborn?
Covid-19-risk for the fetus and the mother examined
In a review article in the journal “Science” a response to that. Et makes two different sides of the infection event visible: the writer Meredith Wadman can calm down – a in the USA, a respected science journalist – mothers-to-be: An infection to the fetus, at least in the later pregnancy is very rare, and experts see also for the early development of the Unborn child is no danger.
but it points to a special risk for the women themselves: more Recent data indicate that the pregnancy could make your body more prone to disease Covid-19, the Sars-CoV-2 caused.
This assessment is based on data from the U.S. Centers for Disease Control and Prevention (CDC), as well as a small in Sweden conducted the study. The CDC had analyzed the history of Covid-19 infections in 91.412 women in the reproductive age. Of 8270 were pregnant. The risk was landing in an intensive care unit, compared with non-pregnant women increased by 50 percent. More to the Coronavirus to 3.5 million infections: Corona fiasco in the United States to stop the phenomenon of Corona-Fatigue: Covid-19-Convalescent suffer for weeks under Extreme-fatigue RKI provides Corona-Symptom-Chaos day-care centres to send healthy children to work from home half of the balance-sheet: 5 Corona-questions to which we urgently need answers to a Complete recovery not sure: Corona-patients suffer for weeks after infection.
Pregnant women have a 70 percent higher risk of need for artificial respiration in a
with Respect to artificial ventilation, the risk was 70 percent higher. The probability of dying remained in the two groups, however, the same. However, this is only a partial view, restricts Wadman. Because pregnancy status was only at 28 percent of 326.000 the CDC until June, reported Covid-19-patients known.
The Swedish health authority took advantage of for their study, the data of all Swedes who were ill in March and April of this year, Covid-19. From this the authors determined the Rate of patients requiring intensive care. Although their number was low: Only 13 of the pregnant women and 40 non pregnant women were spent in intensive care units. However, as a result, it for Pregnant women or women immediately after birth more than six times more likely to land there than it is for members of the non-pregnant comparison group.
the cause could be in the immune system
The cause of the higher susceptibility of experts in the immune system of the expectant situate mothers. “In the case of viral infections, more severe gradients, threaten them, in part, because the whole immune system is designed to start a reaction against the fetus,” says the immunologist Akiko Iwasaki, Yale School of Medicine in “Science”.
“The mother needs to put her own immune system to get the Baby healthy.” Nevertheless, the immune system in pregnancy active, adds to the Virologist Carolyn Coyne, University of Pittsburgh, but an immune response to infection with Sars-CoV-2 “has the potential to be immense complications trigger.”
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lung and cardiovascular system of Pregnant women are stressed, as is
One of the reasons that the pathogen attacks primarily the lungs and the cardiovascular system. These are in a pregnancy but, anyway, under a lot of Stress. This is because, when the uterus is enlarged, leaving less and less room for the lungs, which results in Pregnant women often leading to shortness of breath. In addition, the lung function is impaired.
in addition, Pregnant women need more oxygen and blood to supply the fetus. In late pregnancy, the need up to a 50 percent increase. In the case of a infection, this can multiply the Stress that the Virus exerts on the lungs and the cardiovascular system. “The heart has been working for two,” explained the infectious disease Lodge, David Baud of the University hospital of Lausanne.
“now there is a pathogen known to alter the blood vessels and inflammation triggers, it increases the work load for the heart.” Later in pregnancy, the blood volume, as well as the metabolic activity increases in the organs. This can result in the additional amount of liquid ends up in an infection to unwanted places – such as in the lungs.
another factor is the risk of a severe course for Pregnant women on the rise: her blood tends to clump together more rapidly – probably to limit the blood loss at birth. However, the Coronavirus increases the tendency to clumping. For infected Pregnant women, the risk of a double-threatening shock, because you risk to suffer from closures of important blood vessels, increases immensely.
Covid-19: the danger is not to the birth of over
Even after the birth, the danger is not over yet. The a study a group to the gynecologist Malavika Prabhu conducted by the Weill Cornell Medical College in New York shows. She oversaw 675 Pregnant women, who had arrived in three hospitals low. After the birth, nine out of the 70 women who suffered from Covid-19, complications such as fever and low oxygen content in blood, leading to hospital admissions have developed in.
Other researchers investigated how Covid-19 affects the Unborn. Some viruses, including the causative organisms of Herpes, rubella, as well as the Zika-disease – is known to harm fetuses. In individual cases, Sars seems to attack CoV-2 babies in the mother’s womb. The children’s doctor, Daniele De Luca of the University of Paris Saclay demonstrated in a case study that the pathogen infected in the third Trimester Covid pregnant-19-patient to the fetus.
Apparently, he had penetrated the placental barrier, the baby in the mother’s womb protects substances in the normal case, against microbes and toxins. “Such infections are extremely rare,” says De Luca.
Virologist is confident
The Pittsburgh Virologist Coyne is also optimistic. Thus, while it was still unclear whether fetuses can be damaged by an infection in the sensitive first trimester of Pregnancy, when the tissues and organs develop. The placental barrier is not yet completely developed. “Would the Virus but a destructive pathogen that causes in early pregnancy, malformations, there would have to be in China clear cases”, affirms Coyne.
“there, There was the first major wave of Infection.” Of the “Science” contacted Chinese Doctors have confirmed, to have no congenital anomalies, pointed to a given small numbers of cases, uncertainty about data.
71 mothers ill, none of the babies
infected, A further investigation confirmed this view. In New York, researchers examined nearly 700 babies were born in three hospitals to the world, to Covid-19. In 71 mothers were ill, but none of their children was infected.
This is consistent with the findings that won the epidemiologist Roberto Romero of Wayne State University in placental cells carry the receptor molecules, to the Sars-CoV-2 docks, only very rarely on their surfaces, which makes an infection unlikely. In contrast, the receptors for the Zika and herpes pathogen found frequently.
However, the pathogen in pregnant Covid, can inhibit 19 patients, the growth of the fetuses, such as the New York physicians found. It causes the formation of blood clots, which can clog in the placenta veins. In the study, this was in half of the patients, compared to eleven percent in healthy subjects. The clots decrease the flow of oxygen and nutrients to the fetus.
researchers create a Register with data on Pregnant women
for More clarity about the risks of Covid-19 for Pregnant women is to be a Register (“Pregnancy Coronavirus Outcomes Registry”), which establishes the University of California (UC) in San Francisco just. In it, researchers used the data of 1100 pregnant U.S. women. You will also want to examine what is Anti-Corona medication cause in fetuses.
The UC-midwife Yalda Afshar, who is in charge of the Register, expected for the autumn of this year, a wave of babies that were conceived in the early Phase of the pandemic. “What comes out for the Baby, if the mother has the first eight weeks of embryonic development, Covid-19?”, asks Afshar, according to “Science” itself is pregnant. “The data we need for future births.”
Overall, however apply to the health personnel, this has to do with expectant mothers, a simple recipe, says of the Swiss infection Loge Baud: “to Protect your pregnant patients. You are the first in need of masks, and you should minimize their social contacts.“
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